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Products Details
Product Description
– Anti-inflammatory agent 50 (compound a1) is a Fusidic acid derivative with anti-inflammatory effects. Anti-inflammatory agent 50 inhibits inflammatory factor NO, IL-6 and TNF-α. Anti-inflammatory agent 50 alleviates acute lung injury by regulating inflammatory mediators and suppressing the MAPK, NF-κB and NLRP3 inflammasome signaling pathways[1].
Web ID
– HY-155753
Shipping
– Room temperature
Molecular Formula
– C40H55N3O6
References
– [1]Zheng Liu, et al. Design, synthesis fusidic acid derivatives alleviate acute lung injury via inhibiting MAPK/NF-κB/NLRP3 pathway. Eur J Med Chem. 2023 Aug 1;259:115697.
Molecular Weight
– 673.88
SMILES
– C/C(C)=CCC/C(C(OCC1=CN(C2=CC=CC=C2)N=N1)=O)=C3[C@@H](OC(C)=O)C[C@]4(C)[C@@]5(C)CC[C@@]6([H])[C@H](C)[C@H](O)CC[C@]6(C)C5[C@H](O)C[C@@]/34[H]
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– COX;NF-κB
Pathway
– Immunology/Inflammation;NF-κB
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
