Products Details

Product Description

– Anti-inflammatory agent 17 is a potent and orally active anti-inflammatory agent. Anti-inflammatory agent 17 inhibits the release of IL-6 and TNF-α in vitro experiments without cytotoxicity. Anti-inflammatory agent 17 exhibits anti-inflammatory activity in vivo. Anti-inflammatory agent 17 has the potential for the research of Acute lung injury (ALI)[1].

Web ID

– HY-146547

Shipping

– Room temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C20H23NO5

References

– [1]Wang X,et al. Design, synthesis and bioactivity evaluation of fisetin derivatives as potential anti-inflammatory agents against LPS-induced acute lung injury. Bioorg Med Chem. 2021; 49:116456.

CAS Number

– 2763226-84-0

Molecular Weight

– 357.40

SMILES

– CN(CCCOC1=CC=C(C(C(/C=C/C2=CC(O)=C(C=C2)O)=O)=C1)O)C

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology

Solubility

– 10 mM in DMSO

Target

– Interleukin Related;TNF Receptor

Isoform

– CD40;IL-6

Pathway

– Apoptosis;Immunology/Inflammation

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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