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Products Details
Product Description
– Ansatrienin B (Mycotrienin II) is an ansamycin antibiotic isolated from Streptomyces. Ansatrienin B is active against fungi and yeasts, but inactive against bacteria.Ansatrienin B displays antitumor antibiotic activity and can be used as an ADC Toxin[1][2].
Web ID
– HY-122306
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C36H50N2O8
References
– [1]M Sugita, et al. Studies on Mycotrienin Antibiotics, a Novel Class of Ansamycins. I. Taxonomy, Fermentation, Isolation and Properties of Mycotrienins I and II. J Antibiot (Tokyo). 1982 Nov;35(11):1460-6.|[2]D Feuerbach, et al. Mycotrienins. A New Class of Potent Inhibitors of Osteoclastic Bone Resorption. J Biol Chem. 1995 Oct 27;270(43):25949-55.|[3]Yuriko Yamada, et al.Mycotrienin II, a Translation Inhibitor That Prevents ICAM-1 Expression Induced by Pro-Inflammatory Cytokines. J Antibiot (Tokyo). 2011 May;64(5):361-6.
CAS Number
– 82189-04-6
Molecular Weight
– 638.79
SMILES
– O=C(C1CCCCC1)N[C@@H](C(O[C@@H](C/C=C/C=C/C=C/[C@@H](C2)OC)[C@@H]([C@H](/C(C)=CCCC3=CC(O)=CC(NC2=O)=C3O)O)C)=O)C
Clinical Information
– No Development Reported
Research Area
– Cancer; Infection
Solubility
– 10 mM in DMSO
Target
– Antibiotic;Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
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