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Angelicin
SKU
HY-N0763-10mM/1mL
Category Natural Products
Tags Anti-infection;Apoptosis, Apoptosis;Virus Protease, Cancer
$50 – $80
Products Details
Product Description
– Angelicin is a natural tricyclic aromatic hydrocarbon compound that is structurally related to psoralen and has anti-cancer, anti-inflammatory, anti-viral and other activities. Cytotoxic, IC50: 49.56 μM; inhibits MHV-68, IC50: 5.39 μg/ml (28.95 μM).
Web ID
– HY-N0763
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C11H6O3
References
– [1]Md. Ataur Rahman, Angelicin induces apoptosis through intrinsic caspase-dependent pathway in human SH-SY5Y neuroblastoma cells. Molecular and Cellular Biochemistry
October 2012, Volume 369, Issue 1-2, pp 95-104|[2]Hye-Jeong Cho, et al. Antiviral activity of angelicin against gammaherpesviruses. Antiviral Research
Volume 100, Issue 1, October 2013, Pages 75–83|[3]Fang Liu, et al. Angelicin regulates LPS-induced inflammation via inhibiting MAPK/NF-κB pathways. Journal of Surgical Research
Volume 185, Issue 1, November 2013, Pages 300–309
CAS Number
– 523-50-2
Molecular Weight
– 186.16
Compound Purity
– 99.86
SMILES
– O=C1C=CC2=CC=C(OC=C3)C3=C2O1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 33.33 mg/mL (ultrasonic)
Target
– Apoptosis;Virus Protease
Pathway
– Anti-infection;Apoptosis
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.