Amphotericin X1

SKU HY-136153-Get quote Category Tags , ,

Products Details

Product Description

– Amphotericin X1 is an 13-O-methyl derivative of Amphotericin B with good antifungal activity. Amphotericin X1 inhibits Candida albicans 33/079, C.parapsilosis 937A, Cryptococcus neoformans 451, Aspergillus niger 57A and A.fumigatus with MIC values of 1 μg/mL, 8 μg/mL, 1 μg/mL, 2 μg/mL and 2 μg/mL, respectively[1].

Web ID

– HY-136153

Shipping

– Room temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C48H75NO17

References

– [1]Taylor AW, et al. Synthesis and antifungal selectivity of new derivatives of amphotericin B modified at the C-13 position. J Antibiot (Tokyo). 1993 Mar;46(3):486-93.

CAS Number

– 136135-57-4

Molecular Weight

– 938.11

SMILES

– CO[C@](C[C@@H]1O)(C[C@H](C[C@H]([C@@H](CC[C@H](C[C@H](CC(O[C@H]([C@@H]([C@@H]2O)C)C)=O)O)O)O)O)O)O[C@](C[C@H](/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@@H]2C)O[C@@](O[C@@H]3C)([H])[C@H]([C@H]([C@@H]3O)N)O)([H])[C@@H]1C(O)=O

Clinical Information

– No Development Reported

Research Area

– Infection

Solubility

– 10 mM in DMSO

Target

– Fungal

Pathway

– Anti-infection

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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