Download Files:
Amisulpride (hydrochloride)
SKU
HY-14545A-Get quote
Category Reference compound
Tags Dopamine Receptor, GPCR/G Protein;Neuronal Signaling, Neurological Disease
Products Details
Product Description
– Amisulpride hydrochloride is a dopamine D2/D3 receptor antagonist with Kis of 2.8 and 3.2 nM for human dopamine D2 and D3, respectively.
Web ID
– HY-14545A
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C17H28ClN3O4S
References
– [1]Schoemaker H, et al. Neurochemical characteristics of amisulpride, an atypical dopamine D2/D3 receptor antagonist with both presynaptic and limbic selectivity.
J Pharmacol Exp Ther. 1997 Jan;280(1):83-97.|[2]Pawar GR, et al. Evaluation of antidepressant like property of amisulpride per se and its comparison with fluoxetine and olanzapine using forced swimming test in albino mice. Acta Pol Pharm. 2009 May-Jun;66(3):327-31.
CAS Number
– 81342-13-4
Molecular Weight
– 405.94
SMILES
– CCN1C(CNC(C2=CC(S(=O)(CC)=O)=C(N)C=C2OC)=O)CCC1.Cl
Clinical Information
– Launched
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Dopamine Receptor
Isoform
– D3 Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.