Download Files:
Aminooxy-PEG2-BCN
SKU
HY-145593-Get quote
Category ADC Related
Tags ADC Linker, Antibody-drug Conjugate/ADC Related, Cancer
Products Details
Product Description
– Aminooxy-PEG2-BCN is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Aminooxy-PEG2-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Web ID
– HY-145593
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C19H31N3O6
References
– [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337.
CAS Number
– 2253965-14-7
Molecular Weight
– 397.47
SMILES
– O=C(NCCOCCOCCNC(CON)=O)OCC1C2CCC#CCCC12
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ADC Linker
Isoform
– Cleavable Linker
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– ADC Related
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
Related Products
1000 in stock