Download Files:
Aminomalonic acid
SKU
HY-112052-10 mg
Category Natural Products
Tags Cancer, Endogenous Metabolite, Metabolic Enzyme/Protease
$32 – $150
Products Details
Product Description
– Aminomalonic acid is an amino endogenous metabolite, acts as a strong inhibitor of L-asparagine synthetase from Leukemia 5178Y/AR (Ki= 0.0023 M) and mouse pancreas (Ki= 0.0015 M) in vitro. Aminomalonic acid is a potential biomarker to discriminate between different stages of melanoma metastasis[1][2][3].
Web ID
– HY-112052
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C3H5NO4
References
– [1]Van Buskirk JJ, et al. Aminomalonic acid: identification in Escherichia coli and atherosclerotic plaque. Proc Natl Acad Sci U S A. 1984 Feb;81(3):722-5.|[2]Milman HA, et al. Aminomalonic acid and its congeners as potential in vivo inhibitors of L-asparagine synthetase. Enzyme. 1979;24(1):36-47.|[3]Kim HY, et al. Discovery of potential biomarkers in human melanoma cells with different metastatic potential by metabolic and lipidomic profiling. Sci Rep. 2017 Aug 18;7(1):8864.
CAS Number
– 1068-84-4
Molecular Weight
– 119.08
Compound Purity
– 98.0
SMILES
– O=C(O)C(N)C(O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– H2O : 8.33 mg/mL (ultrasonic)
Target
– Endogenous Metabolite
Isoform
– Human Endogenous Metabolite;Microbial Metabolite
Pathway
– Metabolic Enzyme/Protease
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.