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Amino-PEG4-CH2COOH
SKU
HY-130524-100 mg
Category ADC Related
Tags ADC Linker;PROTAC Linkers, Antibody-drug Conjugate/ADC Related;PROTAC, Cancer
$40 – $190
Products Details
Product Description
– Amino-PEG4-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Amino-PEG4-CH2COOH is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].
Web ID
– HY-130524
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C10H21NO6
References
– [1]Nan JI, et al. Mertk degraders and uses thereof. WO2020010210A1.|[2]Maggie Lu, et al. Linker-drug and antibody-drug conjugate (adc) employing the same. EP3335734A1.
CAS Number
– 195071-49-9
Molecular Weight
– 251.28
Compound Purity
– 98.0
SMILES
– O=C(O)COCCOCCOCCOCCN
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– ADC Linker;PROTAC Linkers
Isoform
– Non-cleavable Linker;PEG Linkers
Pathway
– Antibody-drug Conjugate/ADC Related;PROTAC
Product type
– ADC Related
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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