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Products Details
Product Description
– AM8936 acts as a balanced and potent cannabinoid receptor type-1 (CB1) agonist in functional assays (EC50s of 8.6 and 1.4 nM for rCB1 and hCB1, respectively). AM8936 exhibits high affinity for rat CB1 (rCB1) with Ki of 0.55 nM. AM8936 is a potent and efficacious CB1 agonist in vivo. AM8936 can be used for the research of CNS and metabolic disorders, pain, glaucoma, etc[1].
Web ID
– HY-144827
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C25H33NO3
References
– [1]Ioannis P Papanastasiou, et al. Improved cyclobutyl nabilone analogs as potent CB1 receptor agonists. Eur J Med Chem. 2022 Feb 15;230:114027.
CAS Number
– 2820337-96-8
Molecular Weight
– 395.53
SMILES
– CC1(OC2=C([C@@H]3CC(CC[C@H]31)=O)C(O)=CC(C4(CCC4)CCCCCC#N)=C2)C
Clinical Information
– No Development Reported
Research Area
– Neurological Disease; Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Cannabinoid Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
