Download Files:
AM103
$560 – $4,700
Products Details
Product Description
– AM 103 is a potent and selective FLAP inhibitor, with an IC50 value of 4.2 nM.
Web ID
– HY-14163
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C36H38N3NaO4S
References
– [1]Hutchinson JH, et al. 5-lipoxygenase-activating protein inhibitors: development of 3-[3-tert-butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl]-5-(pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic acid (AM103). J Med Chem. 2009 Oct 8;52(19):5803-15.|[2]Lorrain DS, et al. Pharmacological characterization of 3-[3-tert-butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl]-5-(pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic acid (AM103), a novel selective 5-lipoxygenase-activating protein inhibitor that reduces acute and chronic inflammation. J Pharmacol Exp Ther. 2009 Dec;331(3):1042-50.
CAS Number
– 1147872-22-7
Molecular Weight
– 631.76
Compound Purity
– 99.26
SMILES
– O=C(O[Na])C(C)(C)CC(N1CC2=CC=C(C3=CC=C(OC)N=C3)C=C2)=C(SC(C)(C)C)C4=C1C=CC(OCC5=NC=CC=C5)=C4
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 200 mg/mL (ultrasonic)
Target
– FLAP
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
