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ALX-5407 (hydrochloride)

$88$1,020

Products Details

Product Description

– ALX-5407 ((R)-NFPS) hydrochloride is a selective and orally active glycine transporter GlyT1 inhibitor with an IC50 value of 3 nM. ALX-5407 hydrochloride can be used the research of N-methyl-D-aspartate-receptor function and schizophrenia[1].

Web ID

– HY-10711A

Storage Temperature

– 4°C (Powder, sealed storage, away from moisture)

Shipping

– Room Temperature

Molecular Formula

– C24H25ClFNO3

References

– [1]Atkinson BN, et al. ALX 5407: a potent, selective inhibitor of the hGlyT1 glycine transporter. Mol Pharmacol. 2001 Dec;60(6):1414-20.

CAS Number

– 200006-08-2

Molecular Weight

– 429.91

Compound Purity

– 98.0

SMILES

– FC1=CC=C([C@H](OC2=CC=C(C3=CC=CC=C3)C=C2)CCN(C)CC(O)=O)C=C1.[H]Cl

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– GlyT

Pathway

– Membrane Transporter/Ion Channel;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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