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Products Details
Product Description
– Alternaphenol B2 is a selective IDH1 inhibitor from the coral-derived fungus Parengyodontium album SCSIO SX7W11. Alternaphenol B2 shows inhibitory activity against isocitrate dehydrogenase mutant R132H (IDH1m), with IC50 values of 41.9 μM[1].
Web ID
– HY-N12390
Shipping
– Room temperature
Molecular Formula
– C15H10O6
References
– [1]Li X, Shen W, et al. Alternaphenol B2, a new IDH1 inhibitor from the coral-derived fungus Parengyodontium album SCSIO SX7W11 [published online ahead of print, 2023 Oct 18]. Nat Prod Res. 2023;1-7.
Molecular Weight
– 286.24
SMILES
– OC1=C(C(C(OC2=C3C(O)=CC(CO)=C2)=O)=CC=C1)C3=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Isocitrate Dehydrogenase (IDH)
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
