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Products Details
Product Description
– ALR2-IN-2 is a potent inhibitor of aldose reductase (ALR2), with IC50s of 27 nM and 228 nM for rat ALR2 and ALR1, respectively. ALR2-IN-2 can be used for the research of diabetic complications[1].
Web ID
– HY-151946
Shipping
– Room temperature
Molecular Formula
– C17H11FN2O2S2
References
– [1]Kratky M, et, al. Novel rhodanine based inhibitors of aldose reductase of non-acidic nature with p-hydroxybenzylidene functional group. Eur J Med Chem. 2022 Nov 12;246:114922.
Molecular Weight
– 358.41
SMILES
– FC1=CC=C(C=C1)/C=N/N2C(/C(SC2=S)=C/C3=CC=C(C=C3)O)=O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Aldose Reductase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
