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Products Details
Product Description
– ALR1/2-IN-1 (Compound 6e) is an aldehyde reductase (ALR1) and aldose reductase (ALR2) inhibitor with IC50 values of 3.26 μM and 3.06 μM against ALR1 and ALR2, respectively. ALR1/2-IN-1 shows anticancer activity[1].
Web ID
– HY-147977
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C18H18N4O5S2
References
– [1]Javid N, et al. Exploiting oxadiazole-sulfonamide hybrids as new structural leads to combat diabetic complications via aldose reductase inhibition. Bioorg Chem. 2020 Jun;99:103852.
CAS Number
– 2419233-57-9
Molecular Weight
– 434.49
SMILES
– O=C(NC1=CC=CC=C1OC)CSC2=NN=C(C3=CC=CC=C3NS(=O)(C)=O)O2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Aldose Reductase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
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