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Products Details
Product Description
– ALR1/2-IN-1 (Compound 6e) is an aldehyde reductase (ALR1) and aldose reductase (ALR2) inhibitor with IC50 values of 3.26 μM and 3.06 μM against ALR1 and ALR2, respectively. ALR1/2-IN-1 shows anticancer activity[1].
Web ID
– HY-147977
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C18H18N4O5S2
References
– [1]Javid N, et al. Exploiting oxadiazole-sulfonamide hybrids as new structural leads to combat diabetic complications via aldose reductase inhibition. Bioorg Chem. 2020 Jun;99:103852.
CAS Number
– 2419233-57-9
Molecular Weight
– 434.49
SMILES
– O=C(NC1=CC=CC=C1OC)CSC2=NN=C(C3=CC=CC=C3NS(=O)(C)=O)O2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Aldose Reductase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
