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Products Details
Product Description
– ALR-6 is an antagonist of the 5-lipoxygenase (5-LOX) activating protein FLAP and has anti-inflammatory activity. ALR-6 potently inhibits 5-LOX product formation (>80%) in pro-inflammatory M1-MDM and has no significant effect on direct inhibition of 5-LOX[1].
Web ID
– HY-155407
Shipping
– Room temperature
Molecular Formula
– C18H14O5
References
– [1]Cerchia C et al. Identification of selective 5-LOX and FLAP inhibitors as novel anti-inflammatory agents by ligand-based virtual screening. Eur J Med Chem. 2023 Nov 8;263:115932.
CAS Number
– 6621-92-7
Molecular Weight
– 310.30
SMILES
– COC1=CC=C(C=C1)C2=C/C(C(O2)=O)=C/C3=C(C=C(C=C3)O)O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– FLAP
Pathway
– Immunology/Inflammation
Product type
– Reference compound
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