Alprenolol (hydrochloride)

$79$475

Products Details

Product Description

– Alprenolol ((RS)-Alprenolol; dl-Alprenolol) hydrochloride is an orally active non-selective β-adrenoceptor antagonist and an antagonist of 5-HT1A and 5-HT1B receptors. Alprenolol hydrochloride is used as an anti-hypertensive, anti-anginal and anti-arrhythmic agent[1][2][3].

Web ID

– HY-B1517A

Storage Temperature

– 4°C (Powder, sealed storage, away from moisture)

Shipping

– Room Temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C15H24ClNO2

Citations

– Nat Chem Biol. 2023 Aug 14.|bioRxiv. 2020 Jan.|J Chromatogr B. 2023 Jun 20, 123804.|J Pharmaceut Biomed. 2020, 113870.|Nat Commun. 2020 Sep 25;11(1):4857.

References

– [1]Himori N, et al. Effects of beta-adrenoceptor blocking agents, pindolol, alprenolol and practolol on blood pressure and heart rate in conscious renal hypertensive dogs. Arch Int Pharmacodyn Ther. 1977 Jan;225(1):152-65.|[2]Fernández-Guasti A, et al. Evidence for the involvement of the 5-HT1A receptor in the anxiolytic action of indorenate and ipsapirone. Psychopharmacology (Berl). 1990;101(3):354-8.|[3]Parratt JR, et al. Myocardial and haemodynamic effects of the beta-adrenoceptor blocking drug alprenolol (H56/28) in anaesthetized cats. Br J Pharmacol. 1969 Oct;37(2):357-66.

CAS Number

– 13707-88-5

Molecular Weight

– 285.81

Compound Purity

– 99.76

SMILES

– OC(COC1=CC=CC=C1CC=C)CNC(C)C.[H]Cl

Clinical Information

– Launched

Research Area

– Cancer

Solubility

– DMSO : 100 mg/mL (ultrasonic)|H2O : 50 mg/mL (ultrasonic)

Target

– 5-HT Receptor

Isoform

– 5-HT1 Receptor

Pathway

– GPCR/G Protein;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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