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Products Details
Product Description
– ALPK1-IN-3 is an inhibitor of ALPK1 extracted from patent WO2022063153A1 compound T007. ALPK1-IN-3 inhibits kidney proinflammatory gene expression and improves the survival rate of the animals in sepsis induced acute kidney injury animal model[1]. ALPK1-IN-3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Web ID
– HY-156519
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C20H16F2N4OS
References
– [1]Danyang Liu, et.al. Benzothiazole and quinoline derivatives and their use.
CAS Number
– 2765633-73-4
Molecular Weight
– 398.43
SMILES
– O=C(C1=C(C=C(N2CCNCC2)C=C1F)F)NC3=NC4=C(S3)C=CC=C4C#C
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– NF-κB
Pathway
– NF-κB
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
