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Aloisine RP106
$77
Only 1000 item(s) left in stock.
Products Details
Product Description
– Aloisine RP106 (compound 38) is a potent inhibitor of Cdk1/cyclin B, Cdk5/p25, and GSK3 with IC50s of 0.70µM, 1.5µM, 0.92 µM, respectively[1].
Web ID
– HY-112336
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C17H19N3O
References
– [1]Yvette Mettey, et al. Aloisines, a new family of CDK/GSK-3 inhibitors. SAR study, crystal structure in complex with CDK2, enzyme selectivity, and cellular effects. J Med Chem. 2003 Jan 16;46(2):222-36.
CAS Number
– 496864-15-4
Molecular Weight
– 281.35
SMILES
– COC1=CC=C(C2=C(CCCC)C3=NC=CN=C3N2)C=C1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– CDK;GSK-3
Isoform
– CDK1;CDK5;GSK-3
Pathway
– Cell Cycle/DNA Damage;PI3K/Akt/mTOR;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
