Download Files:
Products Details
Product Description
– ALK5-IN-31 (compound Ex-08) is a selective ALK-5 inhibitor (IC50≤10 nM), inhibits TGF-β-induced SMAD signaling. ALK5-IN-31 has the potential to inhibit growth of tumour in vivo. ALK5-IN-31 can be used in study of proliferative diseases such as cancer, fibrotic diseases, and systemic sclerosis[1].
Web ID
– HY-151281
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C23H23FN8
References
– [1]Bettina FRANZ, et al. Alk-5 inhibitors and uses thereof. Patent WO2022126133A1.
CAS Number
– 2785430-87-5
Molecular Weight
– 430.48
SMILES
– CC1=CC=CC2=C(NC3=NC(NC4=CC=C(N5CCNCC5)C(F)=C4)=NC=C3)C=NN=C12
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– TGF-β Receptor
Pathway
– TGF-beta/Smad
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
