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ALK inhibitor 1
$240 – $1,200
Products Details
Product Description
– ALK inhibitor 1 (compound 17) is a potent pyrimidin ALK inhibitor. ALK inhibitor 1 is a potent inhibitor of testis-specific serine/threonine kinase 2 (TSSK2; IC50=31 nM) and focal adhesion kinase (FAK; IC50=2 nM)[1].
Web ID
– HY-15357
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C23H28BrN7O3S
References
– [1]Jon E Hawkinson, et al. Potent Pyrimidine and Pyrrolopyrimidine Inhibitors of Testis-Specific Serine/Threonine Kinase 2 (TSSK2). ChemMedChem. 2017 Nov 22;12(22):1857-1865.
CAS Number
– 761436-81-1
Molecular Weight
– 562.48
Compound Purity
– 99.62
SMILES
– O=S(C1=C(NC2=C(Br)C=NC(NC3=C(OC)C=C(N4CCN(C)CC4)C=C3)=N2)C=CC=C1)(NC)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 1M HCl : 100 mg/mL (ultrasonic;adjust pH to 1 with HCl)|DMSO : ≥ 100 mg/mL
Target
– Anaplastic lymphoma kinase (ALK);FAK
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
