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Products Details
Product Description
– Alclometasone (7a-Chloro-16a-methyl prednisolone) is a glucocorticoid and inhibits the release of pro-inflammatory mediators from leukocytes. Alclometasone can be used to relieve corticosteroid-responsive dermatoses, including atopic dermatitis, eczema, psoriasis and allergic dermatitis[1].
Web ID
– HY-A0150
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C22H29ClO5
References
– [1]Alclometasone|[2]Nishibe Y, et al. Species and sex differences in the inhibitory action of the corticosteroid alclometasone dipropionate on the hepatic drug-metabolizing system.Jpn J Pharmacol. 1989 Aug;50(4):435-43.
CAS Number
– 67452-97-5
Molecular Weight
– 408.92
SMILES
– C[C@@]12[C@](C(CO)=O)(O)[C@H](C)C[C@@]1([H])[C@]3([H])[C@H](Cl)CC4=CC(C=C[C@]4(C)[C@@]3([H])[C@@H](O)C2)=O
Clinical Information
– Phase 2
Research Area
– Inflammation/Immunology; Cancer
Solubility
– 10 mM in DMSO
Target
– Glucocorticoid Receptor
Pathway
– Immunology/Inflammation;Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
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