Products Details

Product Description

– Alclometasone (7a-Chloro-16a-methyl prednisolone) is a glucocorticoid and inhibits the release of pro-inflammatory mediators from leukocytes. Alclometasone can be used to relieve corticosteroid-responsive dermatoses, including atopic dermatitis, eczema, psoriasis and allergic dermatitis[1].

Web ID

– HY-A0150

Shipping

– Room temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C22H29ClO5

References

– [1]Alclometasone|[2]Nishibe Y, et al. Species and sex differences in the inhibitory action of the corticosteroid alclometasone dipropionate on the hepatic drug-metabolizing system.Jpn J Pharmacol. 1989 Aug;50(4):435-43.

CAS Number

– 67452-97-5

Molecular Weight

– 408.92

SMILES

– C[C@@]12[C@](C(CO)=O)(O)[C@H](C)C[C@@]1([H])[C@]3([H])[C@H](Cl)CC4=CC(C=C[C@]4(C)[C@@]3([H])[C@@H](O)C2)=O

Clinical Information

– Phase 2

Research Area

– Inflammation/Immunology; Cancer

Solubility

– 10 mM in DMSO

Target

– Glucocorticoid Receptor

Pathway

– Immunology/Inflammation;Vitamin D Related/Nuclear Receptor

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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9 * 8 =