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Albendazole
$66 – $73
Products Details
Product Description
– Albendazole (SKF-62979) is an orally active and broad-spectrum parasiticide with high effectiveness and low host toxicity, is used for the research of gastrointestinal parasites in humans and animals. Albendazole induces apoptosis and autophagy in cancer cells. Albendazole also inhibits tubulin polymerization and HIF-1α, VEGF expression, has antioxidant activity, and inhibits the glycolytic process in cancer cells[1][2][3][4][5].
Web ID
– HY-B0223
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C12H15N3O2S
References
– [1]Vural G, et al. Efficacy of novel albendazole salt formulations against secondary cystic echinococcosis in experimentally infected mice. Parasitology. 2020 Nov;147(13):1425-1432.|[2]Li L, et al. Determination of albendazole and metabolites in silkworm Bombyx mori hemolymph by ultrafast liquid chromatography tandem triple quadrupole mass spectrometry. PLoS One. 2014 Sep 25;9(9):e105637.|[3]Pourgholami MH, et al. In vitro and in vivo suppression of growth of hepatocellular carcinoma cells by albendazole. Cancer Lett. 2001 Apr 10;165(1):43-9.|[4]Jung YY, et al. Regulation of apoptosis and autophagy by albendazole in human colon adenocarcinoma cells. Biochimie. 2022 Jul;198:155-166.|[5]Zhou F, et al. Albendazole inhibits HIF-1α-dependent glycolysis and VEGF expression in non-small cell lung cancer cells. Mol Cell Biochem. 2017 Apr;428(1-2):171-178.
CAS Number
– 54965-21-8
Molecular Weight
– 265.33
Compound Purity
– 99.00
SMILES
– O=C(OC)NC1=NC2=CC=C(SCCC)C=C2N1
Clinical Information
– Launched
Research Area
– Cancer; Infection
Solubility
– DMSO : 20 mg/mL (ultrasonic)|H2O : 0.67 mg/mL (ultrasonic)
Target
– Antibiotic;Apoptosis;Autophagy;Bacterial;HIF/HIF Prolyl-Hydroxylase;Microtubule/Tubulin;Parasite;Reactive Oxygen Species;VEGFR
Pathway
– Anti-infection;Apoptosis;Autophagy;Cell Cycle/DNA Damage;Cytoskeleton;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
