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Alaproclate (hydrochloride)
$115
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Products Details
Product Description
– Alaproclate (GEA 654) hydrochloride is a selective and orally active serotonin re-uptake inhibitor (SSRI). Alaproclate hydrochloride also acts as a potent, reversible and noncompetitive antagonist of the NMDA receptor coupled ion flow[1][2].
Web ID
– HY-133732
Shipping
– Room temperature
Molecular Formula
– C13H19Cl2NO2
References
– [1]Campagna J, et al. A small molecule ApoE4-targeted therapeutic candidate that normalizes sirtuin 1 levels and improves cognition in an Alzheimer’s disease mouse model. Sci Rep. 2018 Dec 4;8(1):17574.|[2]Wilkinson A, et al. Alaproclate acts as a potent, reversible and noncompetitive antagonist of the NMDA receptor coupled ion flow.
CAS Number
– 60719-83-7
Molecular Weight
– 292.20
SMILES
– NC(C)C(OC(C)(C)CC1=CC=C(Cl)C=C1)=O.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– 5-HT Receptor;iGluR;Serotonin Transporter
Pathway
– GPCR/G Protein;Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
