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Products Details
Product Description
– Akuammigine is an alkaloid that can be found in hook-bearing branch of Uncariarhynchophylla. Akuammigine is a is a very weak antagonist at pre- and postsynaptic α-adrenoceptor of the rat vas deferens[1][2].
Web ID
– HY-N2833
Shipping
– Room temperature
Molecular Formula
– C21H24N2O3
References
– [1]Yang W, et, al. Almitrine-Raubasine combination for dementia. Cochrane Database Syst Rev. 2011 Mar 16;(3):CD008068.|[2]Qi W, et, al. Alkaloids from the hook-bearing branch of Uncariarhynchophylla and their neuroprotective effects against glutamate-induced HT22 cell death. J Asian Nat Prod Res. 2014;16(8):876-83.
CAS Number
– 642-17-1
Molecular Weight
– 352.43
SMILES
– COC(C1=CO[C@@H](C)[C@]2([H])CN3CCC(C4=CC=CC=C4N5)=C5[C@@]3([H])C[C@]12[H])=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Adrenergic Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Natural Products
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