Akt1/Akt2-IN-1

SKU HY-50862-10 mg Category Tags , ,

$420$2,520

Products Details

Product Description

– Akt1/Akt2-IN-1 (Compound 17) is an allosteric inhibitor of Akt1 (IC50=3.5 nM) and Akt2 (IC50=42 nM), with potent and balanced activity[1].

Web ID

– HY-50862

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Cancer-Kinase/protease

Molecular Formula

– C33H29N7O

References

– [1]Bilodeau MT, Allosteric inhibitors of Akt1 and Akt2: a naphthyridinone with efficacy in an A2780 tumor xenograft model. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3178-82.

CAS Number

– 893422-47-4

Molecular Weight

– 539.63

Compound Purity

– 99.71

SMILES

– O=C(NC=C1)C2=C1N=C(C(C3=CC=CC=C3)=C2)C(C=C4)=CC=C4CN5CCC(CC5)C6=NNC(C7=NC=CC=C7)=N6

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : ≥ 35 mg/mL

Target

– Akt

Isoform

– Akt1;Akt2

Pathway

– PI3K/Akt/mTOR

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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