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AKT-IN-6
$120 – $720
Products Details
Product Description
– AKT-IN-6 (Example 13) is a potent Akt inhibitor. AKT-IN-6 inhibits Akt1, Akt2 and Akt3 with IC50s < 500nM, respectively. (patent WO2013056015A1).
Web ID
– HY-19982
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C22H20FN5O
References
– [1]Taisheng Huang; et al.Isoindolinone and pyrrolopyridinone derivatives as akt inhibitors. WO2013056015A1.|[2]Manning BD, et al. AKT/PKB signaling: navigating downstream. Cell. 2007;129(7):1261-1274.
CAS Number
– 1430056-54-4
Molecular Weight
– 389.43
Compound Purity
– 99.51
SMILES
– N#CC1=C(C2=CC3=C(C(N([C@@H](CC4=CC=CC(F)=C4)CN)C3)=O)C=C2)N(C)N=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 125 mg/mL (ultrasonic)
Target
– Akt
Isoform
– Akt1;Akt2;Akt3
Pathway
– PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
