AK-IN-1

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Products Details

Product Description

– AK-IN-1 (compound 4072-2732) is an adenosine kinase (AK) inhibitor that is competitive for adenosine (Ado) but not for ATP. AK-IN-1 inhibits 86%, 87% and 89% of AK activity at concentrations of 2, 4 and 10 µM, respectively. AK-IN-1 has good potential for research in many disease areas, including ischaemia, inflammation and seizures[1].

Web ID

– HY-148327

Storage Temperature

– 4°C (Powder, protect from light)

Shipping

– Room Temperature

Molecular Formula

– C22H21N3O4

References

– [1]Park J, et al. Identification and biochemical studies on novel non-nucleoside inhibitors of the enzyme adenosine kinase. Protein J. 2007 Apr;26(3):203-12.

CAS Number

– 378775-98-5

Molecular Weight

– 391.42

Compound Purity

– 99.95

SMILES

– OCCNC1=NC=NC2=C1C(C3=CC=C(OC)C=C3)=C(C4=CC=C(C=C4)OC)O2

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology; Neurological Disease; Cardiovascular Disease

Solubility

– DMSO : 100 mg/mL (ultrasonic)

Target

– Adenosine Kinase

Pathway

– Metabolic Enzyme/Protease;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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