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Products Details
Product Description
– AG 538 is a potent, competitive inhibitor of IGF-1 receptor kinase, with an IC50 of 400 nM[1].
Web ID
– HY-135436
Shipping
– Room temperature
Molecular Formula
– C16H11NO5
References
– [1]G Blum, et al. Substrate Competitive Inhibitors of IGF-1 Receptor Kinase. Biochemistry. 2000 Dec 26;39(51):15705-12.
CAS Number
– 133550-18-2
Molecular Weight
– 297.26
SMILES
– N#C/C(C(C1=CC=C(O)C(O)=C1)=O)=CC2=CC=C(O)C(O)=C2
Clinical Information
– No Development Reported
Research Area
– cancer
Solubility
– 10 mM in DMSO
Target
– IGF-1R
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
