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Products Details
Product Description
– AG-045572 is a GnRH receptor antagonist with Kis of 6.0 nM and 3.8 nM for human and rat GnRH receptor, respectively. AG-045572 is metabolized by CYP3A and ressuppresses testosterone[1].
Web ID
– HY-107534
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C30H37NO5
References
– [1]Iatsimirskaia EA, et al. Effect of testosterone suppression on the pharmacokinetics of a potent gnRH receptor antagonist. Pharm Res. 2002 Feb;19(2):202-8.
CAS Number
– 263847-55-8
Molecular Weight
– 491.62
SMILES
– CC1(C2=CC(CC3=CC=C(C(NC4=C(C=C(OC)C=C4OC)OC)=O)O3)=C(C)C=C2C(C)(C)CC1)C
Clinical Information
– No Development Reported
Research Area
– Endocrinology
Solubility
– 10 mM in DMSO
Target
– GnRH Receptor
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
