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Aeruginosin 865
SKU
HY-130994-10mg
Category Natural Products
Tags ADC Cytotoxin;NF-κB, Antibody-drug Conjugate/ADC Related;NF-κB, Cancer; Inflammation/Immunology
Products Details
Product Description
– Aeruginosin 865, isolated from terrestrial cyanobacterium Nostoc sp. Lukešová 30/93, is the first aeruginosin-type peptide containing both a fatty acid and a carbohydrate moiety. Aeruginosin 865 inhibits translocation of NF-kB to the nucleus. Aeruginosin 865 has anti-inflammatory effect[1]
Web ID
– HY-130994
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C41H64N6O14
References
– [1]Aleksandra Kapuścik, et al. Novel Aeruginosin-865 from <i>Nostoc sp</i>. as a potent anti-inflammatory agent. Chembiochem. 2013 Nov 25;14(17):2329-37.|[2]Ivana Veselá, et al. Cytotoxic Effect of Aeruginosin-865, Resveratrol and Capsaicin on Mouse Fibroblasts and Cells Derived from Fallow Deer. Natural Product Communications, Volume: 13 issue: 2.
CAS Number
– 1611990-01-2
Molecular Weight
– 864.98
SMILES
– O=C([C@@H]1[C@@H](O)[C@H](O)[C@H](O)[C@H](O[C@@H]2[C@@H](OC(CCCCC)=O)C[C@@]3([H])C[C@H](C(NCCCCNC(N)=N)=O)N(C([C@H](NC([C@H](O)CC4=CC=C(O)C=C4)=O)CC(C)C)=O)[C@@]3([H])C2)O1)O
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– ADC Cytotoxin;NF-κB
Pathway
– Antibody-drug Conjugate/ADC Related;NF-κB
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.