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Adjudin
$66 – $319
Products Details
Product Description
– Adjudin is an extensively studied male contraceptive with a superior mitochondria-inhibitory effect. Adjudin is also a potent Cl- channel blocker.
Web ID
– HY-18996
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C15H12Cl2N4O
References
– [1]Li K, et al. Inhibition of sperm capacitation and fertilizing capacity by adjudin is mediated by chloride and its channels in humans. Hum Reprod. 2013 Jan;28(1):47-59.|[2]Li X, et al. Combination delivery of Adjudin and Doxorubicin via integrating drug conjugation and nanocarrier approaches for the treatment of drug-resistant cancer cells. J Mater Chem B. 2015 Feb 28;3(8):1556-1564.|[3]Xie QR, et al. Male contraceptive Adjudin is a potential anti-cancer drug. Biochem Pharmacol. 2013 Feb 1;85(3):345-55.
CAS Number
– 252025-52-8
Molecular Weight
– 335.19
Compound Purity
– 98.0
SMILES
– O=C(C1=NN(CC2=CC=C(Cl)C=C2Cl)C3=C1C=CC=C3)NN
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 16.67 mg/mL (ultrasonic)
Target
– Chloride Channel;Mitochondrial Metabolism
Pathway
– Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
