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Product Description
– Acyclovir monophosphate is a potent anti-herpes simplex virus (HSV) agent. Acyclovir monophosphate blocks DNA synthesis through the inhibition of the viral DNA polymerase and terminates the chain elongation of the viral DNA. Acyclovir monophosphate shows antitumor activity[1][2].
Web ID
– HY-17422B
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C8H12N5O6P
References
– [1]Yao J, et al. Turning an antiviral into an anticancer drug: nanoparticle delivery of acyclovir monophosphate. J Control Release. 2013 Sep 28;170(3):414-20.|[2]Elion GB, et al. Mechanism of action and selectivity of acyclovir. Am J Med. 1982 Jul 20;73(1A):7-13.
CAS Number
– 66341-16-0
Molecular Weight
– 305.18
SMILES
– O=C1N=C(NC2=C1N=CN2COCCOP(O)(O)=O)N
Clinical Information
– Launched
Research Area
– Cancer; Infection
Solubility
– 10 mM in DMSO
Target
– Antibiotic;HSV
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
