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Acremoxanthone C
SKU
HY-N10199-Get quote
Category Natural Products
Tags Calmodulin;Endogenous Metabolite, Cardiovascular Disease, Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease
Products Details
Product Description
– Acremoxanthone C is a potent calmodulin (CaM) inhibitor found in Purpureocillium lilacinum. Acremoxanthone C binds to the human calmodulin (hCaM) biosensor hCaM M124C-mBBr, with Kd of 18.25 nM[1].
Web ID
– HY-N10199
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C33H26O12
References
– [1]Madariaga-Mazón A, et al. Absolute configuration of acremoxanthone C, a potent calmodulin inhibitor from Purpureocillium lilacinum. J Nat Prod. 2013;76(8):1454-1460.
CAS Number
– 1360445-63-1
Molecular Weight
– 614.55
SMILES
– CC(O[C@@H]1[C@@]23C(C([C@H](C4=C(O[C@@]5(C(C6=O)=C(C=C[C@H]5O)O)C(OC)=O)C6=C(O)C=C4C3)C=C2)=O)=C(C7=C(O)C=C(C)C=C71)O)=O
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Calmodulin;Endogenous Metabolite
Isoform
– Microbial Metabolite
Pathway
– Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.