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Products Details
Product Description
– Efflux pump-IN-4 is an AcrB efflux pump inhibitor, with ability to potentiate the effect of antibiotics. Efflux pump-IN-4 inhibits Nile Red (a known substrate of AcrB) efflux. Efflux pump-IN-4 does not disrupts the bacterial outer membrane nor display toxicity in a nematode model[1].
Web ID
– HY-149812
Shipping
– Room temperature
Molecular Formula
– C29H34N2O4S
References
– [1]Guo T, et al. Design and synthesis of benzochromene derivatives as AcrB inhibitors for the reversal of bacterial multidrug resistance. Eur J Med Chem. 2023 Mar 5;249:115148.
CAS Number
– 2890177-95-2
Molecular Weight
– 506.66
SMILES
– O=C(N1CCOCC1)C2=CC3=C(C4=C2CCC(C)(C)O4)C=CC=C3OCCCSC5=CC=C(C=C5)N
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial;Parasite
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
