Download Files:
Products Details
Product Description
– AChE-IN-28 (Compound 2h) is a selective slow-binding inhibitor of acetylcholinesterase with an IC50 of 0.2 nM[1].
Web ID
– HY-151927
Shipping
– Room temperature
Molecular Formula
– C33H48BrF3N5O4
References
– [1]Saifina LF, et al. Novel slow-binding reversible acetylcholinesterase inhibitors based on uracil moieties for possible treatment of myasthenia gravis and protection from organophosphate poisoning. Eur J Med Chem. 2022 Nov 24;246:114949.
Molecular Weight
– 715.66
SMILES
– CC[N+](CCCCCN1C(C=CN(C1=O)CCCCCCN(C(C=C2=O)C)C(N2C)=O)=O)(CC3=CC=CC=C3C(F)(F)F)CC.[Br-]
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Cholinesterase (ChE)
Isoform
– AChE
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
