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Products Details
Product Description
– AChE-IN-17 (compound 1) is a potent AChE inhibitor with an IC50 value of 28.98 μM. AChE-IN-17 can significantly prevent H2O2-induced PC12 cell death, exhibiting excellent neuroprotective effect. AChE-IN-17 can be used for researching neurodegenerative diseases (NDs)[1].
Web ID
– HY-N10384
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C25H28O6
References
– [1]Santi MD, et al. Neuroprotective effects of prenylated flavanones isolated from Dalea species, in vitro and in silico studies. Eur J Med Chem. 2020;206:112718.
CAS Number
– 460345-17-9
Molecular Weight
– 424.49
SMILES
– C=CC(C)(C1=CC([C@@H]2CC(C3=C(C=C(C(C/C=C(C)C)=C3O2)O)O)=O)=C(C=C1O)O)C
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Cholinesterase (ChE)
Isoform
– AChE
Pathway
– Neuronal Signaling
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
