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Products Details
Product Description
– AChE-IN-15 (Compound 3d) is a reversible human acetylcholinesterase (huAChE) (IC50=6.8 μM) and human butyrylcholinesterase (huBChE) (IC50=16.1 μM) inhibitor. AChE-IN-15 shows significant antioxidant potency, AChE-IN-15 can be used for the research of Alzheimer’s disease[1].
Web ID
– HY-146039
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C23H24N2O7
References
– [1]Zhipei Sang, et al. Apigenin-rivastigmine hybrids as multi-target-directed liagnds for the treatment of Alzheimer’s disease. Eur J Med Chem. 2020 Feb 1;187:111958.
CAS Number
– 2242792-25-0
Molecular Weight
– 440.45
SMILES
– O=C(OC1=CC=C(C2=CC(C3=C(O)C=C(OC(N(CC)C)=O)C=C3O2)=O)C=C1)N(CC)C
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Cholinesterase (ChE)
Isoform
– AChE;BChE
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
