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AChE/BChE/MAO-B-IN-1
SKU
HY-146312-Get quote
Category Reference compound
Tags Cholinesterase (ChE);Monoamine Oxidase, Neurological Disease, Neuronal Signaling
Products Details
Product Description
– AChE/BChE/MAO-B-IN-1 (Compound 10) is a reversible and non-time-dependent AChE, BChE and MAO-B inhibitor with IC50 values of 7.31, 0.56 and 26.1 μM for hAChE, hBChE and hMAO-B, respectively. AChE/BChE/MAO-B-IN-1 can cross the BBB and shows neuroprotective effects without cytotoxicity[1].
Web ID
– HY-146312
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C20H24N2O2
References
– [1]Košak U, et al. N-alkylpiperidine carbamates as potential anti-Alzheimer’s agents. Eur J Med Chem. 2020 Jul 1;197:112282.
CAS Number
– 2416910-82-0
Molecular Weight
– 324.42
SMILES
– O=C(OCC1CCN(CC1)CC2=CC=CC=C2)NC3=CC=CC=C3
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Cholinesterase (ChE);Monoamine Oxidase
Isoform
– MAO-B
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.