Products Details

Product Description

– AChE/BChE/MAO-B-IN-1 (Compound 10) is a reversible and non-time-dependent AChE, BChE and MAO-B inhibitor with IC50 values of 7.31, 0.56 and 26.1 μM for hAChE, hBChE and hMAO-B, respectively. AChE/BChE/MAO-B-IN-1 can cross the BBB and shows neuroprotective effects without cytotoxicity[1].

Web ID

– HY-146312

Shipping

– Room temperature

Applications

– Neuroscience-Neurodegeneration

Molecular Formula

– C20H24N2O2

References

– [1]Košak U, et al. N-alkylpiperidine carbamates as potential anti-Alzheimer’s agents. Eur J Med Chem. 2020 Jul 1;197:112282.

CAS Number

– 2416910-82-0

Molecular Weight

– 324.42

SMILES

– O=C(OCC1CCN(CC1)CC2=CC=CC=C2)NC3=CC=CC=C3

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– Cholinesterase (ChE);Monoamine Oxidase

Isoform

– MAO-B

Pathway

– Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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