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AChE/BChE-IN-6
SKU
HY-146315-Get quote
Category Reference compound
Tags Cholinesterase (ChE);Monoamine Oxidase, Neurological Disease, Neuronal Signaling
Products Details
Product Description
– AChE/BChE-IN-6 (compound 22) is a potent dual AChE/BChE inhibitor with IC50 values of 0.809 µM, 2.248 µM and > 100 µM for hBChE, hAChE and hMAO-B, respectively. AChE/BChE-IN-6 penetrates the blood-brain barrier (BBB). AChE/BChE-IN-6 can be used for Alzheimer’s disease (AD) research[1].
Web ID
– HY-146315
Shipping
– Room temperature
Molecular Formula
– C23H30N2O2
References
– [1]Košak U, et, al. N-alkylpiperidine carbamates as potential anti-Alzheimer’s agents. Eur J Med Chem. 2020 Jul 1;197:112282.
CAS Number
– 2416910-94-4
Molecular Weight
– 366.50
SMILES
– CC(C1=CC=C(C=C1)NC(OCC2CCN(CC2)CC3=CC=CC=C3)=O)C
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Cholinesterase (ChE);Monoamine Oxidase
Isoform
– AChE;BChE;MAO-B
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.