Products Details

Product Description

– AChE/BChE-IN-6 (compound 22) is a potent dual AChE/BChE inhibitor with IC50 values of 0.809 µM, 2.248 µM and > 100 µM for hBChE, hAChE and hMAO-B, respectively. AChE/BChE-IN-6 penetrates the blood-brain barrier (BBB). AChE/BChE-IN-6 can be used for Alzheimer’s disease (AD) research[1].

Web ID

– HY-146315

Shipping

– Room temperature

Molecular Formula

– C23H30N2O2

References

– [1]Košak U, et, al. N-alkylpiperidine carbamates as potential anti-Alzheimer’s agents. Eur J Med Chem. 2020 Jul 1;197:112282.

CAS Number

– 2416910-94-4

Molecular Weight

– 366.50

SMILES

– CC(C1=CC=C(C=C1)NC(OCC2CCN(CC2)CC3=CC=CC=C3)=O)C

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– Cholinesterase (ChE);Monoamine Oxidase

Isoform

– AChE;BChE;MAO-B

Pathway

– Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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