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AChE/BChE-IN-5
SKU
HY-146665-Get quote
Category Reference compound
Tags Cholinesterase (ChE), Neurological Disease, Neuronal Signaling
Products Details
Product Description
– AChE/BChE-IN-5 (BMC-16) is a dual AChE and BChE inhibitor with IC50 values of 266 nM and 10.6 nM against human AChE (hAChE) and human BChE (hBChE), respectively. AChE/BChE-IN-5 can cross the BBB[1].
Web ID
– HY-146665
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C17H26N2O3
References
– [1]Wu J, et al. Design, synthesis and biological evaluation of novel carbamates as potential inhibitors of acetylcholinesterase and butyrylcholinesterase. Bioorg Med Chem. 2020 Mar 1;28(5):115324.
CAS Number
– 2410992-68-4
Molecular Weight
– 306.40
SMILES
– O=C(OC1=CC=C(C(O)CNC2CCCCC2)C=C1)N(C)C
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Cholinesterase (ChE)
Isoform
– AChE;BChE
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.