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AChE/BChE-IN-15
SKU
HY-149484-Get quote
Category Reference compound
Tags Cholinesterase (ChE), Neurological Disease, Neuronal Signaling
Products Details
Product Description
– AChE/BChE-IN-15 (Compound 6d) is an AChE/BChE inhibitor, with IC50s of 20 nM and 220 nM respectively. AChE/BChE-IN-15 binds to both catalytic anionic site (CAS) and peripheral anionic site (PAS) in the active sites of AChE and BChE. AChE/BChE-IN-15 can be used for research of Alzheimer’s disease[1].
Web ID
– HY-149484
Shipping
– Room temperature
Molecular Formula
– C29H30N6O3
References
– [1]Paptawan Suwanhom, et al. Novel Lawsone鈥換uinoxaline Hybrids as New Dual Binding Site Acetylcholinesterase Inhibitors. ACS Omega 2023.
Molecular Weight
– 510.59
SMILES
– O=C1C(OCCCCCCCCN2N=NC=C2CNC3=CC=C4N=CC=NC4=C3)=CC(C5=C1C=CC=C5)=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Cholinesterase (ChE)
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.