Products Details

Product Description

– AChE/BChE-IN-15 (Compound 6d) is an AChE/BChE inhibitor, with IC50s of 20 nM and 220 nM respectively. AChE/BChE-IN-15 binds to both catalytic anionic site (CAS) and peripheral anionic site (PAS) in the active sites of AChE and BChE. AChE/BChE-IN-15 can be used for research of Alzheimer’s disease[1].

Web ID

– HY-149484

Shipping

– Room temperature

Molecular Formula

– C29H30N6O3

References

– [1]Paptawan Suwanhom, et al. Novel Lawsone鈥換uinoxaline Hybrids as New Dual Binding Site Acetylcholinesterase Inhibitors. ACS Omega 2023.

Molecular Weight

– 510.59

SMILES

– O=C1C(OCCCCCCCCN2N=NC=C2CNC3=CC=C4N=CC=NC4=C3)=CC(C5=C1C=CC=C5)=O

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– Cholinesterase (ChE)

Pathway

– Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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