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ACDPP
SKU
HY-103564-Get quote
Category Reference compound
Tags GPCR/G Protein;Neuronal Signaling, mGluR, Neurological Disease
Products Details
Product Description
– ACDPP is a specific mGluR5 antagonist. ACDPP partially bolcks the increase of fragile X mental retardation protein (FMRP) caused by DHPG (HY-12598A) (group I mGluR Agonist)[1].
Web ID
– HY-103564
Shipping
– Room temperature
Molecular Formula
– C12H13ClN6O
References
– [1]Wang H, et al. Roles of calcium-stimulated adenylyl cyclase and calmodulin-dependent protein kinase IV in the regulation of FMRP by group I metabotropic glutamate receptors. J Neurosci. 2008 Apr 23;28(17):4385-97.
CAS Number
– 37804-11-8
Molecular Weight
– 292.72
SMILES
– O=C(C1=NC(Cl)=C(N(C)C)N=C1N)NC2=NC=CC=C2
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– mGluR
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.