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Acamprosate (calcium)
$66 – $73
Web ID
– HY-17030
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C5H10NO4S.1/2Ca
References
– [1]Preuss UW.
Commentary on the study: impact of depressive symptoms on future alcohol use in patients with co-occurring bipolar disorder and alcohol dependence: a prospective analysis in an 8-week randomized controlled trial of acamprosate (Prisciandaro et al.).
Alcohol Clin Exp Res. 2012 Jun;36(6):967-9. doi: 10.1111/j.1530-0277.2012.01827.x.|[2]Witkiewitz K, Saville K, Hamreus K.
Acamprosate for treatment of alcohol dependence: mechanisms, efficacy, and clinical utility.
Ther Clin Risk Manag. 2012;8:45-53.|[3]Gahr M, et al.
Relapse prevention in alcohol dependence: acamprosate and naltrexone as a combined pharmacological strategy.Nervenarzt. 2012 Aug 15.|[4]Palucha-Poniewiera A, Pilc A.
Involvement of mGlu5 and NMDA receptors in the antidepressant-like effect of acamprosate in the tail suspension test.
Prog Neuropsychopharmacol Biol Psychiatry. 2012 Oct 1;39(1):102-6.|[5]Hinton DJ, et al.
Ethanol withdrawal-induced brain metabolites and the pharmacological effects of acamprosate in mice lacking ENT1.
Neuropharmacology. 2012 Jun;62(8):2480-8.
CAS Number
– 77337-73-6
Molecular Weight
– 200.24
Compound Purity
– 98.0
SMILES
– CC(NCCCS([O-])(=O)=O)=O.[0.5Ca2+]
Clinical Information
– Launched
Research Area
– Neurological Disease
Solubility
– DMSO : < 1 mg/mL|H2O : 100 mg/mL (ultrasonic)
Target
– GABA Receptor
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
