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Ac-Lys-Val-Cit-PABC-MMAE (formic)
$450 – $1,500
Products Details
Product Description
– Ac-Lys-Val-Cit-PABC-MMAE (formic) is a agent-linker conjugate for ADC. Ac-Lys-Val-Cit-PABC-MMAE contains the ADC linker (peptide Ac-Lys-Val-Cit-PABC) and a potent tubulin polymerization inhibitor Monomethyl auristatin E (HY-15162)[1].
Web ID
– HY-147286A
Storage Temperature
– -20°C (Powder, sealed storage, away from moisture and light)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C67H110N12O16
References
– [1]Kleniman, et al. Engineered polypeptide conjugates. WO2015015448A2.
Molecular Weight
– 1339.66
Compound Purity
– 99.96
SMILES
– O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC3=CC=C(C=C3)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC([C@@H](NC(C)=O)CCCCN)=O)=O)=O)=O)=O)=O)=O)OC)=O.OC=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 200 mg/mL (ultrasonic;warming)
Target
– Drug-Linker Conjugates for ADC
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– ADC Related
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
