Products Details

Product Description

– ABT-639 hydrochloride is a novel, peripherally acting, selective T-type Ca2+ channel blocker.

Web ID

– HY-101616

Shipping

– Room temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C20H21Cl2F2N3O3S

References

– [1]Jarvis MF, et al. A peripherally acting, selective T-type calcium channel blocker, ABT-639, effectively reduces nociceptive and neuropathic pain in rats. Biochem Pharmacol. 2014 Jun 15;89(4):536-44.

CAS Number

– 1235560-31-2

Molecular Weight

– 492.37

SMILES

– O=S(C1=CC(C(N2C[C@](CCC3)([H])N3CC2)=O)=C(Cl)C=C1F)(NC4=CC=CC=C4F)=O.Cl

Clinical Information

– Phase 2

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– Calcium Channel

Isoform

– T-type calcium channel

Pathway

– Membrane Transporter/Ion Channel;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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