Abemaciclib metabolite M20

SKU HY-129336-10 mg Category Tags , ,

$350$2,250

Products Details

Product Description

– Abemaciclib metabolite M20 (LSN3106726), the active metabolite of Abemaciclib, is a selective CDK4/6 inhibitor for the treatment of cancer[1].

Web ID

– HY-129336

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Cancer-Kinase/protease

Molecular Formula

– C27H32F2N8O

References

– [1]Morschhauser F, et al. Clinical activity of abemaciclib in patients with relapsed or refractory mantle cell lymphoma – a phase II study. Haematologica. 2021;106(3):859-862. Published 2021 Mar 1.

CAS Number

– 2138499-06-4

Molecular Weight

– 522.59

Compound Purity

– 96.02

SMILES

– OCC1=NC2=C(F)C=C(C3=NC(NC4=NC=C(CN5CCN(CC)CC5)C=C4)=NC=C3F)C=C2N1C(C)C

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : 5 mg/mL (ultrasonic)

Target

– CDK

Isoform

– CDK4;CDK6

Pathway

– Cell Cycle/DNA Damage

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

My Cart
Close Wishlist
Close Recently Viewed
Categories

Please fill out this form to request the file. We will send it to your Email address shortly. Thanks.

Please enable JavaScript in your browser to complete this form.

=

Please fill out this form to request the pricing.
We will send it to your email address shortly.
Thanks.

Please enable JavaScript in your browser to complete this form.

=