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Products Details
Product Description
– ABCB1-IN-1 (compound 3) is a potent ABCB1 inhibitor. ABCB1-IN-1 induces cell apoptosis. ABCB1-IN-1 bearing 1-benzylimidazole has IC50 values of 1.26 μM and 2.21 μM for Colo205 and Colo320 cells, respectively[1].
Web ID
– HY-149366
Shipping
– Room temperature
Molecular Formula
– C36H33F3FeN2O4PS
References
– [1]Adhan Pilon, et al. First iron(II) organometallic compound acting as ABCB1 inhibitor. Eur J Med Chem. 2023 Aug 5;256:115466.
Molecular Weight
– 733.54
SMILES
– C[Fe]([N]1=CN(CC2=CC=CC=C2)C=C1)([C]=O)[P](C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5.FC(F)(S(=O)([O])=O)F.c6cccc6
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– P-glycoprotein
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
