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Products Details
Product Description
– ABCB1-IN-1 (compound 3) is a potent ABCB1 inhibitor. ABCB1-IN-1 induces cell apoptosis. ABCB1-IN-1 bearing 1-benzylimidazole has IC50 values of 1.26 μM and 2.21 μM for Colo205 and Colo320 cells, respectively[1].
Web ID
– HY-149366
Shipping
– Room temperature
Molecular Formula
– C36H33F3FeN2O4PS
References
– [1]Adhan Pilon, et al. First iron(II) organometallic compound acting as ABCB1 inhibitor. Eur J Med Chem. 2023 Aug 5;256:115466.
Molecular Weight
– 733.54
SMILES
– C[Fe]([N]1=CN(CC2=CC=CC=C2)C=C1)([C]=O)[P](C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5.FC(F)(S(=O)([O])=O)F.c6cccc6
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– P-glycoprotein
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
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