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Products Details
Product Description
– AB10 is a selective S1R antagonist. AB10 with Ki of 10, 165 nM for S1R and S2R, respectively. AB10 reverses the effect of Capsaicin (HY-10448) caused pain in model[1].
Web ID
– HY-149855
Shipping
– Room temperature
Molecular Formula
– C23H30N2
References
– [1]Dichiara M, et al. Synthesis, Computational Insights, and Evaluation of Novel Sigma Receptors Ligands. ACS Chem Neurosci. 2023 May 17;14(10):1845-1858.
Molecular Weight
– 334.50
SMILES
– C1(CN(CC2=CC=CC=C2)C3)C3CCCN1CCCC4=CC=CC=C4
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– Sigma Receptor
Isoform
– Sigma 1 Receptor;Sigma 2 Receptor
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
