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Products Details
Product Description
– AB-729 sodium is a siRNA specifically designed to inhibit viral replication and reduces HBV antigens[1][2]. AB-729 conjugates to a trimer of N-acetylgalactosamine (GalNAc) ligand that promotes uptake into hepatocytes via the asialoglycoprotein receptor (ASGR).
Web ID
– HY-132603A
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C502H640F6N162Na38O303P38S6
References
– [1]Efthymios P Tsounis, et al. Toward a new era of hepatitis B virus therapeutics: The pursuit of a functional cure. World J Gastroenterol. 2021 Jun 7;27(21):2727-2757.|[2]Arbutus Receives Authorization to Proceed with an Investigational New Drug Application (IND) for AB-729, its Proprietary Subcutaneously-Delivered RNAi Agent.
CAS Number
– 2826248-50-2
Molecular Weight
– 16148.44
SMILES
– [AB-729 (sodium)]
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in H2O
Target
– HBV;Small Interfering RNA (siRNA)
Pathway
– Anti-infection;Epigenetics
Product type
– Oligonucleotides
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
